联系方式
邮箱：hxm@hit.edu.cn
个人简介
2000-2004年：西北大学 理学学士
2005-2008年：吉林大学 理学硕士
2008-2011年：吉林大学 理学博士
2011-2021年：哈尔工业大学 讲师
2017-2018年：韦恩州立大学 访问学者
Personal Profile
2000-2004年：Northwest University Bachelor Degree
2005-2008年：Jilin University Master Degree
2008-2011年：Jilin University Doctor of philosophy
2011-2021年：Harbin Institute of technology Lecturer
2017-2018年：Wayne State University Visiting Scholar
研究方向和领域
Abnormality of Protein Degradation
研究内容
蛋白质降解异常与疾病的关系及相关的非编码RNA调控
The role and noncoding RNA regulation of abnormal protein degradation in pathologic process
研究成果
1. Xuemei Huang; Jiapeng Wang; Lili Cui; Xiaohuan Zou; Yingjiu Zhang; Recombinant GST-I-Aβ28-induced efficient serum antibody against Aβ42, Journal of Neuroscience Methods,2010, 186(1): 52-59.
2. Lili Cui*, Xuemei Huang, Jiapeng Wang, Yingjiu Zhang；Specific and efficient anti-Aβ42 antibodies induced by sixteen tandem repeats of Aβ9, Journal of Neuroimmunology, 2010, 227: 18–25.
3. Jianquan Guo, Xuemei Huang, Hui Wang, Huanjie Yang; Celastrol Induces Autophagy by Targeting AR/miR-101 in Prostate Cancer Cells, PLoS One, 2015,Oct 16;10(10):e0140745.
4.Hui Wang* , Kai Li , Yu Mei , Xuemei Huang , Zhenglin Li , Qingzhu Yang , Huanjie Yang；Sp1 Suppresses miR-3178 to Promote the Metastasis Invasion Cascade via Upregulation of TRIOBP, Mol Ther Nucleic Acids, 2018,Sep 7:12:1-11.
5. Yuran Gao*; Zhicheng Zhang; Kai Li; Liying Gong; Qingzhu Yang; Xuemei Huang; Chengcheng Hong; Mingfeng Ding; Huanjie Yang; Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells. Cell Death Dis, 2017 Jul 13;8(7):e2924.
6. Qingzhu Yang*; Kai Li; Xuemei Huang; Chen Zhao; Yu Mei; Xinyuan Li; Lin Jiao; Huanjie Yang; lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF β-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer. Mol Ther Nucleic Acids,2020 Mar 6;19:974-985.
7. Kush Pate; Zainab So Ahmed; Xuemei Huang; Qianqian Yang; Elmira Ekinci ; Christine M Neslund-Dudas; Bharati Mitra;,Fawzy Aem Elnady ; Young-Hoon Ahn ; Huanjie Yang; Jinbao Liu; Qing Ping Dou; Discovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition, Future Med Chem, 2018 Sep 1, 10(17):2087-2108.
8. Isel Castro*; Elmira Ekinci; Xuemei Huang; Hassan Ali Cheaito; Young-Hoon Ahn; Jesus Olivero-Verbel; Q Ping Dou; Proteasome-associated cysteine deubiquitinases are molecular targets of environmental optical brightener compounds. J Cell Biochem.
开设的课程
生物化学B
Biochemistry B
皮肤的生物学化学基础
Biochemical Basis of Skin
